⇚ Regimen OPDIVO® and YERVOY® with Limited Course Chemotherapy - for Non Small Cell Lung Cancer Medical Name OPDIVO® (Nivolumab) and YERVOY® (Ipilimumab) with 2 cycles of TAXOL® (Paclitaxel) and PARAPLATIN® (Carboplatin) - for advanced NSCLC Cycles Given N/A Delivery Phases N/A Special Instructions Chemotherapy with TAXOL® and PARAPLATIN® is for 2 cycles only, for rapid disease control of Lung Cancer. Both OPDIVO® and YERVOY® are administered for 2 years or until disease progression or unacceptable toxicity. Monitor closely for immune mediated end organ damage such as Pneumonitis, Colitis, Hepatitis, Nephritis and Endocrinopathies. References Reck M, et al. ASCO Meeting 2020 - VIEW Drug Mode Given Standard Dose Days to Be Given Frequency Solution Volume Duration OPDIVO® (Nivolumab) IV 360 mg D1 q21 NSS 250 cc 60 minutes YERVOY® (Ipilimumab) IV 1 mg/kg D1 q42 NSS 250 cc 60 minutes TAXOL® (Paclitaxel) IV 225 mg/m2 D1 q21 NSS 500 cc 180 minutes PARAPLATIN® (Carboplatin) IV AUC 5 D1 q21 NSS 250 cc 60 minutes